Research & Discovery The latest research news in genetics and genomics. Exome Sequencing Study Suggests Early Menopause May Not Be Monogenic The findings, based on exome sequencing of 104,733 post-menopausal women in the UK Biobank, show that early menopause may be a polygenic condition. Space Travel Shifts White Blood Cell Expression in Transcriptomic Study Researchers saw immune-related gene expression changes in astronauts on the International Space Station, along with shifts to baseline in the weeks after their return to Earth. ACMG Adds Three New Genes to Secondary Findings List The American College of Medical Genetics and Genomics has added three new cardiovascular genes to the latest release of its secondary finding list. Proteomics Firm Pixelgen Targeting Fall Release of Single-Cell Spatial Analysis Tech Premium The company is working with early-access users and recently published a preprint detailing use of the system to map cell surface proteins in T cells. Bio-Techne to Acquire Swiss Spatial Biology Firm Lunaphore Lunaphore offers its Comet end-to-end spatial biology platform that integrates staining, imaging, and image pre-processing steps into a high-throughput instrument. Jun 21, 2023 Gut Microbiome Differences Highlighted Between Industrialized, Non-Industrialized Populations Jun 21, 2023 Recent Tech Advancements Provide Large Leap Forward for Mass Spec-Based Plasma Proteomics Premium Jun 20, 2023 Human-Specific Features Found With CRISPR Screening on Stem Cells Jun 16, 2023 Study Compares Abilities of Various Genetic Approaches to Identify Drug Targets Jun 16, 2023 With $50M Investment in MOSAIC Project, Owkin Seeks to Become Cancer 'Drug Discovery Enterprise' Premium Jun 15, 2023 Hand Condition Contributors Include Variants Passed Down From Neanderthals Jun 14, 2023 Northwestern Team's Top-Down Mass Spec Approach Can Analyze 1K Single Cells per Day Premium Jun 14, 2023 Consortium Produces Pangenome Reference Spanning Dozens of Chinese Populations Jun 14, 2023 MGI Tech Partners With Sweden's Xpress Genomics on Single-Cell RNA-seq Tech Development Jun 14, 2023 Calviri Tries New Approach to Cancer Dx, Vaccines With Frameshift Peptides Premium Jun 13, 2023 Prostate Cancer Study Suggests High Performance of Polygenic Risk Score Based on Small Variant Set Jun 12, 2023 DNA Methylation Study Finds Association Between Biological Aging, Adverse Childhood Experiences Jun 12, 2023 SomaLogic, Citogen Partner on Services in Spain, Southern Europe Jun 9, 2023 GWAS Links Human Voice Pitch to Gene Influencing Cardiovascular, Hormonal Processes Jun 8, 2023 GA4GH to Focus on Clinical Use of Genomic Data With Strategic Refresh Premium Jun 8, 2023 Single-Cell Atlas of Human Lung Highlights Differences Between Healthy, Diseased States Jun 8, 2023 Institute for Protein Innovation, Addgene Partner to Improve Antibody Access Jun 7, 2023 Lunaphore Technologies, Cell Signaling Technology Partner on Antibody-Based Spatial Proteomics Jun 7, 2023 DeepMind's AlphaFold Seeing Uptake for Protein-Protein Interaction Work Premium Jun 7, 2023 Harvard, Church Lab Broke Promise to NIH on Open Spatial Tech Licensing, Vizgen, NanoString Allege Premium Load More Breaking News Helix, St. Luke's University Health Network Partner on Population Health Study Exome Sequencing Study Suggests Early Menopause May Not Be Monogenic New Products Posted to GenomeWeb: Tempus, GenScript, RealSeq Biosciences, 23andMe People in the News at Biocept, Arcensus, TATAA Biocenter, Quantum-Si, LetsGetChecked, More In Brief This Week: Qiagen, Mainz Biomed, Quest Diagnostics, Haystack Oncology, Becton Dickinson The Scan Cystatin C Plays Role in Immunosuppression, Cancer Immunotherapy Failure, Study Finds A study in Cell Genomics provides insight into how glucocorticoids can lead to cancer immunotherapy failure via cystatin C production. Aging, Species Lifespan Gene Expression Signatures Overlap An Osaka Metropolitan University team reports in Nucleic Acids Research that transcriptional signatures of aging and maximum lifespan have similarities. Splicing Subgroup Provides Protocols for Evaluating Splicing Variant Data The group presents their approach on how to apply evidence codes to splicing predictions and other data in the American Journal of Human Genetics. Single-Cell Transcriptomic Atlas of Mouse Cochlea to Aid Treatment Development Researchers in PNAS conducted single-cell and single-nuclear sequencing of about 120,000 cells at three key timepoints in cochlear development to generate a transcriptomic atlas.