Mass Spectrometry
News on mass spectrometry technology and applications in genetics, genomics, and molecular diagnostics.
Significant recent improvements in depth of coverage and throughput have substantial implications for both researchers and companies in the space.
While the method is still in its early stages, it points the way toward a very high-throughput workflow for top-down single-cell proteomics.
While computing power remains a challenge, AI-based methods could complement existing tools like mass spectrometry and yeast two-hybrid systems.
The new instruments could substantially boost proteomic analyses and address challenges in applications including single-cell and plasma proteomics.
The work indicates the potential of mass spectrometry for proteogenomic applications that have been dominated by affinity-based platforms.